Inhaler Tester--NGI

Sample Preparation (NGI Gentle Rocker)  

A significant number of procedures performed during inhaler testing are highly repetitive and their performance can lead to bottlenecks which compromise overall laboratory operations and efficiency.

Relatively simple and inexpensive sample recovery tools have been designed to alleviate such problems and to ensure testing is carried out in a consistent, reproducible and controlled fashion.

The NGI Gentle Rocker, for example, is a simple economical device for gently agitating the contents of the NGI collection cups in order to dissolve the active drug in the solvent prior to analysis.

The unit comprises a pivoting platform specifically designed to accept the NGI cup collection tray linked to a synchronous motor drive unit and controller.

In operation, the Gentle Rocker rocks back and forth about a central longitudinal axis. The resulting constant motion helps to dissolve the drug in a controlled manner freeing up analyst time for other tasks.

For comprehensive product details, specifications and part numbers, please request a copy of our brochure “Quality Solutions for Inhaler Testing”.

Cup Coating (NGI) 

Particle bounce and re-entrainment can be a particular problem when using cascade impactors to measure the aerodynamic particle size distribution (APSD) of orally inhaled and nasal drug products.

Particle bounce is a phenomenon whereby the particle impacts against the collection surface appropriate to its size but rather than adhering to that surface “bounces” back into the air stream whereupon it is re-entrained and passes to a lower stage than that intended.

The normal method of addressing this problem is to coat the collection surfaces with a tacky viscous material such as, for example, glycerol or silicone oil.

The amount, uniformity and method of application are critical parameters within the coating process.

The NGI Cup Coater has been designed as a standardised approach to this problem and eliminates many of the variables inherent in this process.

For comprehensive product details, specifications and part numbers, please request a copy of our brochure “Quality Solutions for Inhaler Testing”.